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ZD 7155 hydrochloride
🥰Excellent
Catalog No. T13390Cas No. 146709-78-6
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
ZD 7155 hydrochloride
🥰Excellent
Purity: 99.23%
Catalog No. T13390Cas No. 146709-78-6
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $51 | In Stock | |
| 5 mg | $122 | In Stock | |
| 10 mg | $197 | In Stock | |
| 25 mg | $372 | In Stock | |
| 50 mg | $578 | In Stock | |
| 100 mg | $833 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $127 | In Stock |
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Purity:99.23%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist. |
| In vivo | ZD 7155 (240 ng/kg ; 10 min infusion ; SD rats) is approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response.[1] ZD 7155 (1.082 μmol/kg ; administered intravenously) and angiotensin II given at 240 ng/kg (in a 10-min infusion) could suppress the angiotensin II-induced pressor response.[1] ZD 7155 (1.082 mumol/kg ; conscious SHRs) and losartan (6.495 mumol/kg) as intravenous boluses indicate that both ZD 7155 and the reference compound losartan exhibit a significant antihypertensive effect.[1] |
| Molecular Weight | 474.98 |
| Formula | C26H27ClN6O |
| Cas No. | 146709-78-6 |
| Smiles | Cl.CCc1cc2N(Cc3ccc(cc3)-c3ccccc3-c3nn[nH]n3)C(=O)CCc2c(CC)n1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 3.8 mg/mL (7.9 mM ), Sonication and heating to 60℃ are recommended. DMSO: 225.0 mg/mL (473.7 mM ), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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